SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '333509784ff41a9f4dc5d14f81a65f1b33d3929d8b8f8100ae9aa9982f5a964b' 
  AND token = 'wKTfeyHQ2X3Jk4YcqBiBVF3YMK6tL0ysNZfYPK2ePdc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}