SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bf2daeb8aa112d5f537d75901727c03a50cef275d3125a62cbaca161f8e5bd8a' 
  AND token = '43GQ0hXQBCv6kl+fKV252W4AD+S8Jz8d4uaOBARz8G8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}