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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '946466c8c1ef847d467f1871989c43cd24be1ffbfd923c1e38b1d992c8422c1c' 
  AND token = 'Z8eVFpVDf95vWyHDgqFCUM5DUPpYIyo7LruzDY0H2VM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}