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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd19024b99c2f29c09fc2bf060ec8807e2eff4775fd2614d320f0711d027b6624' 
  AND token = '/WiqyzuZLOQ/82CxU9DtNmMtDFGO1OSUZD5JkNon+5k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}