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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b37bed22802f0ed72e74f96c949c74dfe7b057ee19eadbd306344cc0ba6d6198' 
  AND token = 'R2Rw5S+7lfLY72RN/LZI0DumV1XK5HSW2yk24BqjgXE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}