SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab5472607e0dbcec3ddf9c744d0361d85a8d8690e506fa7b6b1448f553068544' 
  AND token = 'NXQ52NV+G2ze0UOXfF8WOOMwxo42Yfbz8qgKDkzPnV4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}