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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28f43e723d2afab38fa31bc9c6044b89cf5bd83c557e127cdc5f7c168d80155e' 
  AND token = 'XamAELgOR2H4VcLI6QlQBWxz79LXVDosDOmlxAj34Wc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}