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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39d1447d29b9fbec53577798ff1e5dd7dbe3e3647ca5f9a49797342ad4555525' 
  AND token = '+fRV0tu+w41rGKKIprciXzjw95ufizC6JtHauTfHVxI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}