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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a94ef33bfd55c1e5baa0b308b605bffd7cb6009e5d8e640477818df2ad625bc2' 
  AND token = 'Fa2E/CVECKZ0041yD1xsyU2/D5WsUqTNrlO3z8fT66M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}