SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '382ab46c6ad96e9b9dadf9ff5179f74a9a3a526a77b42c4070198165cc1ac24b' 
  AND token = 'ns6oIJ9YKCDiYbnwhUNUVyXCGVtqEOkU31bNHGC91YE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}