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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8eee60d995362177ab6fde183ae27caa5c9a27dbe163100a60cfd653026d9e53' 
  AND token = 'rEVyUtgE/oulaQ8zogRJEayXUPPKHKrsrShoIsT5aXg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}