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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '70fbff97935b901c2e05c9dedad416597f2bb71d9ae55dde8cf49b877c1c2644' 
  AND token = 'Iggiw7wnM2OgclBcLWtd29SoZ4+SUg0XbFCO1q1SteA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}