SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cc0e06ca8806eb9f1d975f7c02980b4616e390a48effae8b56198e49c87990e' 
  AND token = 'Ym7hfM1ZOKkyQuGelgOqB1bLMfd+QahxDLZKlG0DzJg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}