SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33c63bce8d23a858d1575d76af3d496dfa322931abbc202a373892e143e0ef81' 
  AND token = 'TX65UmhkgR+JxLuJ0/ptS7QWUrFg9HdWqTXszJ2cUOE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}