SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa4225c3d4a4f710cc0e534b09bd06fad8bd426a0cae06ad0240fa01fa953523' 
  AND token = 'f9EQ/xR0ny5NG3dsRtAo2SXkZeprDkemIIWnQOpWeqU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}