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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c73727acfb42608e80f1ad72d5e18b2acff69708596d0b384c5de44237822f2f' 
  AND token = 'WJaJXacVuTQHPi2/Z5Aqf9KPsQUGuK0fU1E9wLe18Wo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}