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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9657211afef61851f12fb50dbf55a25cfb4275544e79c61f2c73d00665a6c23f' 
  AND token = '+niVALpO8VbhQYJEeQY+cDUnoV/b+/y4XtdmRLb8554=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00067

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}