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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b9eed2653ca43d34443a2298cfcc7f99758e5a7c9dc0b2526e16d2c819e5b305' 
  AND token = 'ulzNubJ9fFtNcE+nIywFON9ON0aiVKcapzlHYDj4thU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}