SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a1c059d4f31deff947553665096c0e5a6ba965cf5d1699705ab4410e2b2a629' 
  AND token = 'usXWum1YPY6B35q0kS7lpGkRs1HRuGXpvCsESbYVpVM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}