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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9111b35375e95ba49bf59e32c5093c8c3d6c11a3d1d9cde6465b5d7c69720a2c' 
  AND token = 'fe/ufWUO8xgA2+UiS6MTbStlAJmXcfG1AIF6KY0s3Ew=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}