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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fdebcc221715c0679c8bedfdb44ecb3883ec1ef6114a79a8a3de9785f3bfce6' 
  AND token = '5WsooWpkCTnAPu7+D1IuzkPrE8mdENbJzVCLnRncVDU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}