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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d454488e29383a4d8e7d4f56042acd0fd334b58fb37dd06ec5637d2a476cdc0' 
  AND token = 'j4TvtTLYuyqU9cljsSze2VHC0BJ5Hm+yZk7RRHqQ+MA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}