SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cea61ae2cc4104952299ba5365eb03a988b7cdabbfd64ae9da24802ca7b967a4' 
  AND token = 'khRw0q0tSJkx4pasvhuDG5RpmPWGNOwYRk5gwhyC5mk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}