SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff73a97eab1b7432fae07acaf484cb5d1ba69a45c0dee086c46b23703f0b84af' 
  AND token = 'YzUmBTr2Rtj6uOgRgRBSUBingj/Pe9X00ekDqdjHZr0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}