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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f91e8294bf266085e97ac4acada5eb1dd20c3a56665e437ffc5bb86182051729' 
  AND token = 'XE2fdrlPzcNrRimrbRiHUwt4xF1byDUAlfP9GJuVYgo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}