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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53e3c570eab837354019956aa0f53be5563a212889a3b24bc8e7e9914efa4e76' 
  AND token = 'U2p7GkfySTubwYR7Ftij97TeKx0+8fccouw+RM6LiM8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}