SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a1372d8e629f8c83dc1b2b4b9f36584145b3ab063565ecca33878360bf34ac9' 
  AND token = '0lYBm/W2213Y8bnyoN3AFgjWlCGfIncFrkn3AOm0E9U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}