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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff0cde9043975dfba3495e4c364386038e1a0d196ff3871a52090c9baec4ed86' 
  AND token = 'gHuBTysKFdyIuytMmmdi8QCPLTVhOrx+qyrsUfcPqvo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}