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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b4449915ce31a48d0bc94694e8ec6356d1c86c8e0be184b67778899e16b4d7e' 
  AND token = 'aK87UmdWqc4BmR/5fH0o/JEUT3lx1pmM2OH1Qdl98Ws=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}