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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e83360768d68bf0565e436bf0f270eecd22bdf2776b2608334eea5cb0552ca57' 
  AND token = 'vtEK7yGAOjiQ9fsJrM6hbG7pf0+X0elgckaJOWYbSB4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}