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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a6be47547ecabc4704851af3dfc075eff4e5b7766981c115366e79859ad0ff2' 
  AND token = 'Osxe+AKRumu7MoA8MwOGL8YVi0Y9WqspLyXPSYsoxQI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}