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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '363bfe4b4465b252293b485f1ef18d4867e12a3681e70a5f25c33778dbecc57a' 
  AND token = 'aj5DwnuffMmBMHFkAOBeYQDzN0EE/0z1G9z/HmABcSQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}