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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c322c2c377cd3ff8056085d3a6f408d6403eb90c2f8313e5d59f244c8c8ba622' 
  AND token = 'Kmkdsk2P02kfDXv4GlAOGxbFPBuqXeEgkqSJOiVlcM4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00100

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}