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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '361acc90dde8f0a3d4e462125c8f9f35b2d1b53514121aa90c414052e43b45cd' 
  AND token = 'BhNI7BrLKvhd5PxQ44cXM+exyQY/5pz9Tsk3aI3goaE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}