SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '537dd02c82f0daeff037c75f48eecce05c23cd64f5ee395b344dcfd5be45f8a0' 
  AND token = 'YTOnnVMfNAx1pZvNS5LeAJ2Vggk69LqKlWKYC3G/V3Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}