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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9073bd74d97f0d7c110295db1099d61eff79cd84da314be7d1f5f9d4a4e85bc' 
  AND token = 'gHxB3p47yh2/iGyrVLH5URECxu2+xTvEu/qZmm6D+eE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}