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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ecd8c20cc8aba48ce3251d72f512aa0ba5cfac1fda56b323b883b511c968850' 
  AND token = 'ZGG0gMsNLVe7VQqDxTPZlOUSaTKtymUbn0zyeSqDNNQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}