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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '13e112e6c6123d7e6a8f164e825eb53d2b6875d9be44f6eb2a2fe7180afa65b1' 
  AND token = 'qyu3hr9+HL9kE1wASlKAoOULlzBtjYagbWrp0EbgoAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}