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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9422f1148b762c21965e143c3eb466f940830e5b7cdf82cf1fa8166aa6d6df0c' 
  AND token = 'y1Pp+2aEdRWgkDFRDFIJr6UUn5LkK2wz8so/hsayc7Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}