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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b81db7431374b58625398f068f6a9b82d111d3522015556b4af3cfc13d4c09b' 
  AND token = 'R1RusLhMwLKm+nqJH3Ah5M+ZbN9l2tO5ytmSXdx5/9U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}