SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc1ac969a405c199809bb47027dcb756235ee9b327fc71de68159635e97c03b4' 
  AND token = 'qeaMy8mG7T1+Fl9P76ESLeHH5B6Bqfgk9G780XAyV3U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}