SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d4c7d49f44b37d160cebc342b06605ead2521449a39fb9b48eb4df5cf4ee97c' 
  AND token = '5RSE2T0v0fZxKMzc7stlgct2wfT76zX7uPp8wG69iwQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}