SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67cc7329b491d92b0b4c58a7300f4d005adcab2b42ab544d6c63aa5f48251617' 
  AND token = '+zP4eY96ksrl23sGu5Z/I9P5y3ZTjxAn/jZKPoUz/Ng=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}