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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8390cbbaeb4ebfc39797feae4c4f711c8a8af46a987325815de40069a694a0f' 
  AND token = 'opSlMbJVkkpSEDUnWuexKLkIZO1RfyS611pueurP4Nk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}