SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05ad38de5ac1127031f84521715e5c1441a62b3b606de6080a60e7fa4e1b9664' 
  AND token = 'GmOmCOQVrbhsHuc0WNy1sa1684WfcffFfhFQ7e0Qr48=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}