SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86143de4cfc187cca267c42cbef3875c57e98ef0738aed9861c00b962b3f48f0' 
  AND token = 'ZW40Cn9SlxtG9L7qiRfY8cDXkpIXqfKIWbJJhLyOpZk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}