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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0071d117e7bb7215a1c2bc0fa8b962b873498a301afea526eb946d40a6479cc' 
  AND token = '4NyrqbE1ti0MXQ2oGEwXjtQumcc+hkoDlmKJbtvjgzI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}