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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '598eceeb3b054718aa422b99fd151f78b5c5f2b97ef9f0b5688c31437870c4ae' 
  AND token = 'y9G75fmKIFVeSjT4hxtrtwW+oTejIuYIOjpiYFtT/Rw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}