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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca5ad04034ac9990efcf74c140a19b7593324a247f4d968b07e89511f8288875' 
  AND token = 'oENuG5Y6c+3GmMGG8LTZ6y5WYJ65Y5xpw+rphXDTdAY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}