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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e8054ea54f951827eecfd6985c5660e71d3be3dcca2cefaf103cc6a6113563a' 
  AND token = '6O6q9Jq7z+zBzd4ybaO/bR1wzYIGIE72nYDNVcE1MzI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}